Fecobionics Publications (April 2025)

 

 

  1. Gregersen H, et al. Fecobionics: Integrating anorectal function measurements. Clin Gastroenterol Hepatol 2018;16:981-983.
  2. Gregersen H, Lo KM. What is the Future of Impedance Planimetry in Gastroenterology? J Neurogastro Motility 2018;24:166-181.
  3. Sun D, Huang Z, Zhuang Z, Ma Z, Lo KM, Liao D, Gregersen H. Fecobionics: A novel bionics device for studying defecation. Ann Biomed Eng 2019;47:576-589.
  4. Liao D, Chen SC, Lo KM, Zhao J, Futaba K, Gregersen H. Theoretical tools to analyze anorectal mechanophysiological data generated by the Fecobionics device. J Biomech Eng 2019 Jun 26. doi: 10.1115/1.4044134.
  5. Gregersen H, Chen SC, Futaba K, Leung WW, Wong C, Mak T, Ng S. Novel Fecobionics defecatory Function Testing. Clin Trans Gastroenterol 2019;10:e00108. https://doi.org/10.14309/ctg.0000000000000108
  6. Sun D, Liao D, Chen SS, Wong C, Leung WW, Futaba K, Mak T, Ng S, Gregersen H. Mechanophysiological analysis of anorectal function using simulated feces in human subjects. Journal of Advanced Research 2020;28:245-254. https://doi.org/10.1016/j.jare.2020.07.002. IF 7.0.
  7. Chen SC, Futaba K, Leung WW, Wong C, Mak T, Ng S, Gregersen H. Simulated Stool for Assessment of Anorectal Physiology. Am J Physiol Gastrointest Liver Physiol 2020;319(4):G462-G468. doi: 10.1152/ajpgi.00242.2020.
  8. Gregersen H, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K. Fecobionics Characterization of Patients with Fecal Incontinence. Clin Gastroenterol Hepatol 2021;19:2447-2449. doi: 10.1016/j.cgh.2020.10.043.
  9. Gregersen H, Wang Y, Guo X, Field F, Nelson M, Combs W, Wang M, Kassab GS. Simulated colonic feces reveals novel contraction patterns. Gastroenterology 2021;160:660–662. PMID: 33181140
  10. Gregersen H. Novel bionics assessment of anorectal mechanosensory physiology. Bioengineering 2020 Nov 14;7(4):E146. doi: 10.3390/bioengineering7040146.PMID: 33202610.
  11. Wang Y, Sun D, Han L, Wang M. Bionic measurement of defecation in a swine model. Physiol Meas 2021 Mar 11;42(2):024003. doi: 10.1088/1361-6579/abe100. PMID: 33508807
  12. Zhuang Z, Hung HY, Chen SC, Futaba K, Gregersen H. Translating Fecobionics into a technique that addresses clinical needs for objective perineal descent measurements. Clin Transl Gastroenterol 2021;12:e00342. PMID: 33956418
  13. Chen SC, Futaba K, Leung WW, Wong C, Mak T, Ng S, Gregersen H, Gregersen H. Effect of Position on Defecatory Efficacy in Normal Subjects. Tech Coloproctol 2021 Mar 29. doi: 10.1007/s10151-021-02439-2. PMID: 33779850
  14. Gregersen H. Bionic Devices and Measurements in the Digestive Tract. Physiol Meas 2021;42(5). https://doi.org/10.1088/1361-6579/ac0313 PMID: 34140432
  15. Gregersen H, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K. Characterization of Patients with obstructed defecation and slow transit constipation with a simulated stool. Clin Gastroenterol Hepatol. 2021;19:2447-2449. Epub 2020 Oct 28.PMID: 33127594
  16. Gregersen H, Sun D, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K, Kar Man Lo, Kassab GS. New developments in defecatory studies based on biomechatronics. J Advanced Res 2022;35;1-11 https://doi.org/10.1016/j.jare.2021.05.005
  17. Kassab GS, Gregersen H, Sun D, Huang Z. Novel Bionics Developments in Gastroenterology: Fecobionics assessment of lower GI tract function. Physiol Meas 2021;42. doi: 10.1088/1361-6579/ac023c. PMID: 
  18. Chen SC, Futaba K, Leung WW, Wong C, Mak T, Ng S, Gregersen H. Functional anorectal studies in patients with low anterior resection syndrome. Neurogastroenterol Motil 2022;34(3):e14208. doi: 10.1111/nmo.14208.
  19. Futaba K, Chen SC, Leung WW, Wong C, Mak T, Ng S, Gregersen H. Fecobionics evaluation of biofeedback therapy in patients with fecal incontinence. Clin Transl Gastroenterol 2022 Apr 1. Online ahead of print. PMID:
  20. Gregersen H, Wang Y, Field F, Wang M, Lo KM, Guo X, Combs W, Kassab G. Feasibility study of defecation studied with a wireless Fecobionics probe in normal subjects. Phys Reports 2022 10, e15338. https://doi.org/10.14814/ phy2.15338.
  21. Futaba K, Chen SS, Leung WW, Wong C, Mak T, Ng S, Gregersen H. Fecobionics Characterization of Patients with Fecal Incontinence. Nature Scientific Reports 2022 Jun 22;12(1):10602. doi: 10.1038/s41598-022-14919-y.
  22. Gregersen H, Wang Y, Field F, Wang M, Lo KM, Guo X, Combs W, Kassab GS. Anorectal volume-pressure relations, contraction work, and flow during simulated defecation. BMMB 2022;21:1613-1621. doi: 10.1007/s10237-022-01610-4. PMID:
  23. Lo KM, Sun D, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K, Gregersen H. Repeatability of defecatory function studies using the Fecobionics device. Dig Dis Sci 2023;68(6):2501-2507. doi: 10.1007/s10620-023-07889-2. PMID: 
  24. Gregersen H, Mittal RK. Rectal contractility in patients with fecal incontinence and obstructed defecation compared to normal subjects. Gastro Hep Adv 2023;2:656-659. doi: 10.1016/j.gastha.2023.03.002. Epub 2023 Mar 9. PMID:
  25. Sun D, Gregersen H. Novel functional endoscopy for visualization of the anorectal junction and anal canal. Tech Innovations Gastrointestinal Endoscopy (TIGE) 2023;25:297-299. DOI 1016/j.tige.2023.03.006. PMID: 37727500.
  26. Sun D, Lo KM, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K, Gregersen H. Consistency of feces affects defecatory function. J Neurogastroenterol Motility. Published onlineMarch 27, 2024. https://doi.org/10.5056/jnm22177
  27. Gregersen H, Sun D, Field F, Combs W, Christensen P, Mousa H, Moawad F, Eisenstein S, Kassab GS. Fecobionics in Proctology. Surgery Open Digestive Advance 12 (2023) 100117. Published preprint https://hal.science/hal-04188997.
  28. Sun D, Lo KM, Chen A, Leung WW, Wong C, Mak T, Ng S, Futaba K, Gregersen H. The rectum, anal sphincter and puborectalis muscle show different contraction wave forms during deferment of simulated feces. Nature Scientific Reports 2024, 14, 432. https://doi.org/10.1038/s41598-023-50655-7.
  29. Sun D, Bao S, Yao H, Hu Y, Huang Z, Ran P,Bao L, Gregersen H. Bionic concepts for assessment of defecatory function and dysfunction. Techniques in Coloproctology (2025) 29:86. https://doi.org/10.1007/s10151-025-03125-3.
  30. Gregersen H, Patel B, Guo X, Barron del Solar G, Eisenstein S, Kassab GS. Anorectal Friction Force Is Reduced in Fecal Incontinence.    Gastro Hep Advances 2025;4:1–3.